Israel's
Nobel Prize Winners in 2004:
Professor Avram Hershko, Professor Aaron Ciechanover
 |
 |
| Professor Aaron Ciechanover
(1947-) |
Professor Avram Hershko
(1937-) |
| Reproduced with permission from the
Haifa Technion (C). |
Professors Aaron Ciechanover (1947-) and Avram
Hershko (1937-) share the 2004 Nobel Prize for Chemistry with
Professor Irwin Rose (USA) for contributing "ground-breaking knowledge"
in "discoveries of ubiquitin-related protein degeneration"
(The "Ubiquitin System"), identifying the staged process in
cells to be marked for destruction - as published in 1978 and pursued
in the 1980s. This discovery has opened the way to major progress in
research on treatment of malignancies, asthma, and degenerative diseases
over the past decade.
The Nobel Chemistry lectures take place at 12:00 on Wednesday,
December 8th 2004, in the Aula Magna, Stockholm University, Stockholm
Sweden. The Nobel Prize Award Ceremony is on Friday, December 10th,
in Stockholm Concert Hall at 16:00 followed by the Nobel Banquet in
Stockholm City Hall at 19:00.
Both Israel's Nobel winers work at the Bruce Rappaport Institute and
Faculty of Medicine at the Israel Technion in Haifa and previously received
the coveted Lasker Award for Basic Medical Sciences for their discovery
in 2002, so that they were surprised to be awarded the Nobel Prize for
Chemistry for the same research.
Both are recipients of the Israel prize: Hershko in 1994 (Biochemistry
and Medicine) and Ciechanover in 2003.
They also shared the Wachter Prize from the University of Innsbruck,
Austria, in 1999. Hershko received the Wolf Prize for Medicine in 2001.
The period in which they worked together was from 1977-1981, while Aaron
Ciechanover was studying for his Ph.D. under Professor Hershko, which
he received in 1981-2. Hershko was awarded a Ph.D. in 1969.
Another interesting fact is that both completed their M.D. at the Hadassah
Hebrew University School of Medicine prior to their IDF service: Hershko
in 1965 and Ciechanover in 1974. Ciechanover also completed an M.Sc. in
1971, on the way to his M.D.
Mabat Sheni, IBA Channel 1, devoted part of the the programme on Monday
November 29th 2004 to their lives, achievements, approaches and the importance
of excellence in Israel, creating portraits of them as bio-medical and
bio-chemical researchers, personalities in their own right, in their professional
and family environment, beyond the realms of conventional biography:
Professor Hershko was born in Hungary in 1937. His family survived the
Shoah, coming to Israel in 1950, and he grew up in Jerusalem in a traditional
home, filled with books and learning, where economies were made in order
to invest in the children's education. His grandfather was a rabbi and
his father a chazan, but he himself is not musical, although he enjoys
classical music. Totally dedicated to research, he feels that Israel's
scientific incubation away from the international research limelight prevented
others from copying their research and claiming the fame. He is philosophical
about the time it took to find the key to protein breakdown, as the quintessence
of the meticulous and painstaking processes of bio-medical research. He
does not see the Nobel Prize as an endpoint, and wishes to continue in
research, rather than make guest appearances and attend conferences in
his capacity as a distinguished person. His wife of 40 years is also a
professional colleague.
Professor Ciechanover was born in Haifa in 1947 to an immigrant family
from Poland and lost his parents during his school years. He was brought
up by his aunt, but clearly recalls the emphasis on books and study in
his parents' home, as well as retaining a strong and vital attachment
to Jewish prayer and chazzanut. Formerly a student and collaborator of
Professor Hershko, he now heads his own research laboratory at the Haifa
Technion.
He is very outspoken on the need for all-round education and promotion
of excellence to ensure Israel's very survival as a state, through its
technological advantage, and of excellence in other fields, such as sport,
music and the arts. A fast-talking, energetic interviewee, Ciechanover
is a person of wide-ranging general and personal interests, but avoids
public engagement on political issues.
Read more:
English
http://md.technion.ac.il/inner/nobel.htm
-
links (NB: links to English language newspaper articles no longer current)
http://www.technion.ac.il/~rapinst/ciechanover.html
http://www.technion.ac.il/~rapinst/hershko.html
http://nobelprize.org/chemistry/laureates/2004/index.html
http://www.laskerfoundation.org/awards/library/2000basic_info.shtml
http://www.aquanet.co.il/wolf/wolf6.html
Hebrew
Haaretz
http://www.haaretz.co.il/hasite/spages/485771.html
Ynet
http://www.ynet.co.il/articles/0,7340,L-2986404,00.html
Maariv
http://www.nrg.co.il/online/1/ART/793/225.html
Nobel Institute
http://nobelprize.org/chemistry/laureates/2004/press-he.pdf
Ciechanover - Israel Prize 2003
http://cms.education.gov.il/EducationCMS/Units/PrasIsrael/
Tashsag/Tzechanover/KorotHaimAromTzechanover.htm